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  • The selective jak1/3-inhibitor r507 mitigates obliterative airway disease both with systemic administration and aerosol inhalation 

    Deuse, Tobias; Hua, Xiaoqin; Stubbendorff, Mandy; Spin, Joshua M.; Neofytou, Evgenios; Taylor, Vanessa; Chen, Yan; Park, Gary; Fink, James B.; Renne, Thomas; Kiefmann, Martina; Kiefmann, Rainer; Reichenspurner, Hermann; Robbins, Robert C.; Schrepfer, Sonja (Ovid Technologies (Wolters Kluwer Health), 2016-05-01)
    Background. The efficacy of selective Janus kinase 1/3 inhibitor R507 to prevent obliterative airway disease was analyzed in preclinical airway transplantationmodels. Methods. Orthotopic trachea transplantations were ...