NUI Galway Theses
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Depositing Your PhD Thesis in ARAN
1. Discuss with your supervisor whether an embargo period to withhold access to your thesis is necessary and, if required, request this using the Library Submission form EOG051 which you you submit with your hardbound thesis.
2. Check whether you need to obtain permissions to include any third party copyrighted material such as illustrations or tables from other sources that you have reproduced. Your ethesis will be available on open access so if you do not have permission you must replace this content in the electronic version with a placeholder that states the content has been removed due to copyright restrictions. You can find further information on third party copyright here and adapt the template permission request letter
3. The electronic version of your thesis may require editing to indicate third party copyright permissions or you should replace third party material with a placeholder where copyright permission was not received before deposit. The thesis should be saved as a PDF and the recommended file naming convention is yearnamedegree.pdf (e.g. 2011smithphd.pdf).
4. When ready to upload the electronic version of the thesis, email aran@nuigalway.ie to request a password for your ARAN account to be created. Please provide your name, school, supervisor and email address in this email.
5. On notification that an account has been created, you should log on to ARAN at http://aran.library.nuigalway.ie using your email address.
- Complete stub metadata: Name, Title, Year, Supervisor, etc.
- Upload the third party copyright cleared version of your thesis as a PDF file.
- Sign off the deposit agreement electronically, including the declaration that third party permissions have been received to complete the deposit.
6. ARAN staff will verify the metadata and will check the status of any embargo request before committing your thesis to ARAN, thus making it available via the Web. [NOTE: Where an embargo has been granted, only the descriptive information will be displayed in ARAN for the duration of the embargo period.]
7. If an embargo period was granted, ARAN staff will lift the access restriction when the embargo period expires.
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Supramolecular ‘Glues’ for protein recognition and assembly
(NUI Galway, 2019-12-06)Supramolecules such as calixarenes, cucurbiturils and foldamers are rapidly emerging as tools for protein assembly. This thesis builds on past successes with some of these scaffolds. Previously, sulfonato-calix[4]arene was ... -
A statistical decision support system incorporating personalised adaptive reference ranges for longitudinal monitoring in prostate cancer
(NUI Galway, 2019-12-05)The overall aims of this thesis are to use modern approaches in Biostatistics to help clinicians diagnose Prostate Cancer (PCa) early, and treat effectively, and to help patients choose between treatment options. Biostatistics ... -
Heterocyclic chemistry: Controlled unmasking of nitric oxide and nitroxides
(NUI Galway, 2019-11-29)Nitric oxide (NO) is a gaseous free radical with medicinally significant properties. The NO-releasing prodrug, isosorbide-5-mononitrate (Is5N), is long established for the treatment of angina pectoris. Nitroxides are organic ... -
Split luciferase reporters of apoptosome formation: a bio-tool to identify new drug-like molecules
(NUI Galway, 2019-12-03)Formation of apoptosome, a key multiprotein complex in mitochondrial-mediated apoptosis, is an essential step during normal development and deregulation of this event is associated with pathological conditions. The apoptosome ... -
Hydrogen peroxide and hydrohalic acid mediated synthesis of halogenated benzimidazolequinones and anti-cancer evaluation of benzotriazinones
(NUI Galway, 2019-11-29)Chapter 1 provides a literature review of metal and metal-free oxidative annulations employed to access ring-fused benzimidazoles while highlighting their significance and application towards anti-tumour benzimidazolequinones. ... -
Pobal sa naoú haois déag á athrú agus á nua-aoisiú
(NUI Galway, 2019-11-18)Léargas ar phobal daoine a lonnaigh ar chósta thiar theas Chonamara, i nGarmna agus sa gCillín, agus arbh éigean dóibh tabhairt faoi athruithe agus nua-aoisiú le linn an naoú haois déag, idir athruithe ar úinéireacht ... -
Optogenetic investigations into the role of glutamatergic neurons of the anterior cingulate cortex in sensory and affective components of pain
(NUI Galway, 2019-11-15)Pain consists of sensory-discriminative and affective-motivational components, which can share a reciprocal relationship. The anterior cingulate cortex (ACC) plays an important role in top-down control and the affective ... -
Developing climate smart agriculture: Insights from Indonesia, Vietnam, Malawi and Ireland
(NUI Galway, 2019-11-18)The present and future challenges to agricultural development and food security are immense. The agricultural sector is a significant driver of climate change, but at the same time, is highly vulnerable to its impacts. ... -
Acquisition of dielectric properties of tissues in the microwave range
(NUI Galway, 2019-11-12)This thesis aims to conduct an investigation into the factors that influence the measurement and interpretation of the dielectric properties of biological tissues in the microwave frequency rage. Firstly, a novel two-stage ... -
Spatially explicit economic and environmental optimisation of bio-SNG production systems integration with the Irish gas network
(NUI Galway, 2019-11-08)Biomass-derived synthetic natural gas (bio-SNG), produced from biomass through gasification and cleaning and conditioning of syngas, is an energy carrier compatible with the existing gas infrastructure and appliances, is ... -
Fibrin-in-fibrin intervention for enhanced dopaminergic graft survival in Parkinson’s disease: Special focus on brain N-glycans
(NUI Galway, 2019-11-07)Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder caused due to the selective loss of dopaminergic neurons in substantia nigra pars compacta (SN) translating into the classical motor symptoms ... -
Effects of remote ischaemic preconditioning on vascular and general surgery patients’ outcomes
(NUI Galway, 2017-09-29)Remote ischaemic preconditioning (RIPC) has been suggested as a non-invasive treatment option in many recent studies. The focus of this thesis is to evaluate the possible effect of this on major health problems in vascular ... -
Provenance of Triassic sandstones in NW European Margin Basins - reconstructing palaeogeography using a multi-proxy approach
(NUI Galway, 2019-11-04)Provenance studies endeavour to unravel the history of a sediment, from investigating potential source rocks, to assessing the processes which may have affected sediment during weathering, transport, burial and diagenesis, ... -
Identifying novel drug therapies for acute myeloid leukaemia by targeting the interactions between leukaemia cells and bone marrow microenvironment
(NUI Galway, 2019-10-25)Acute myeloid leukaemia (AML) is a malignancy caused by a block in differentiation in which aberrant leukemic stem cells drive the production of undifferentiated or partially differentiated leukemic blast cell clones. ... -
Shared leadership and team effectiveness: A social network analysis in the project life cycle
(NUI Galway, 2019-10-25)Many organizations are encouraging a shared leadership approach that meets the increased complexity of today’s working environment. It is therefore imperative for scholars to clearly comprehend the nature and mechanism of ... -
Impact of light intensities and low temperature on the composition and diurnal use of transient carbon stores in barley (Hordeum vulgare)
(NUI Galway, 2019-10-18)The carbon partitioning and accumulation are critical for biomass formation in plants and can be affected by environmental changes and regulated by circadian clock. Thus, in this study, barley was grown under three light ... -
Rethinking China’s mental health law reform: Treatment decision-making and the UN Convention on the Rights of Persons with Disabilities
(NUI Galway, 2019-10-24)This thesis explores China’s mental health law reform regarding treatment decision-making in the new era of the UN Convention on the Rights of Persons with Disabilities (CRPD). It adopts a socio-legal approach, not only ... -
Science classroom discourse and learning in secondary biology classrooms implementing a Content and Language Integrated Learning (CLIL) approach
(NUI Galway, 2019-05-28)This multiple case study research analyses upper secondary teachers’ and students’ experiences of learning biology through the medium of a foreign language, which in this study is English, in the European context (German ... -
The Bangladesh National Blindness and Low Vision Survey - Identification of prevalence, causes and the need for eye care services
(NUI Galway, 2019-10-15)Background: Bangladesh is a densely populated, impoverished country in South Asia with inadequate health service provision for a variety of diseases including treatable ocular conditions. The aims of this comprehensive ... -
Piezoelectric scaffolds: Mediating tendon regeneration by activation of piezosensitive receptors
(NUI Galway, 2019-09-15)Tendon disease caused by trauma, illness or age-related degeneration constitutes an unmet clinical need. Tendon repair using different pharmacological and engineering strategies based on both synthetic and biological grafts ...