Browsing NUI Galway Theses (PhD Theses) by Title
Now showing items 1292-1311 of 1682
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Radiobiological modelling in Radiation Oncology
(2011-09-30)Biological models potentially o er the ability to predict the response of tumour control to irradiation. A tumour control probability (TCP) model with excellent radiobiological pedigree was developed and examined to predict ... -
A rational computer-aided drug discovery approach to target IRE1 and PERK: Insights into structural dynamics and selectivity
(NUI Galway, 2020-05-18)Cells constantly monitor the number of misfolded proteins they accumulate. The accumulation of misfolded proteins in the endoplasmic reticulum (ER) triggers an evolutionarily conserved signaling pathway called the unfolded ... -
(Re)Conceptualising vulnerability in international refugee law and practice: An exploration of the value of a more dynamic approach to vulnerability in refugee status determination
(NUI Galway, 2020-05-07)This thesis investigates whether a reconceptualisation of the concept of vulnerability is required in order to ensure that the needs of ‘vulnerable’ asylum seekers are accommodated in national refugee status determination ... -
(Re)connecting children with nature? A sociological study of environmental education in Ireland.
(2014-11-01)The outcome of environmental education to solve the ecological crises by producing an environmentally sustainable society is uncertain. The marginalisation of environmental education in mainstream education, its precarious ... -
(Re)Thinking the Girl Effect: A Critical Analysis of Girls' Political Subjectivity and Agency at the United Nations 54th Session of the Commission on the Status of Women (CSW 54)
(2012-10-26)This study is a feminist poststructuralist analysis of the Girl Effect informed by girls experiences at the 54th Session of the Commission on the Status of Women (CSW 54). Based on a series of in-depth qualitative interviews ... -
Re-directing George Bernard Shaw: Exploring the staging of Shaw's play-texts for contemporary audiences through practice as research
(NUI Galway, 2019-10-08)At the convergence of performance studies and Shavian studies, this thesis explores the staging of Shaw’s play-texts for contemporary audiences through Practice as Research (PaR). This document charts and analyses three ... -
Re-place: performative landscapes as conceptual ecological environments
(2016-09-27)This dissertation aims to integrate Irish theatre history into a wider discourse of the environmental humanities. Combining material ecocritical thinking and theories of space and place, this thesis contends firstly, that ... -
Reaching beyond the microcosm: Casting recognition-based systems of engagement and exchange as essential for the appropriate development of alternative agriculture
(NUI Galway, 2020-06-17)This thesis seeks to identify recognition-based systems of engagement and exchange within current alternative food networks and hopes to demonstrate how these fluid micro-structures are fundamental to the development of ... -
Readership and Non-Canonical Victorian Popular Fiction 1860-1900: Materiality, Textuality, and Narrative
(2013-12-12)Scholars of print media are increasingly realising significant headway in the recovery of the history of reading. The study of Victorian fiction has also expanded beyond a core body of canonical texts to encompass a more ... -
Reading building: A Gadamerian account of architecture
(NUI Galway, 2020-02-27)This thesis brings Gadamer’s philosophy of art to bear on the experience of built space. I argue that Gadamer’s philosophical hermeneutics, as an approach that proposes understanding as situated and relational, is applicable ... -
Real-time detection of pedestrians in night-time conditions using a vehicle mounted infrared camera
(2016-09-30)Current statistics show that a significant number of road fatalities occur during night-time hours despite a smaller number of vehicles on the road. This number could be significantly reduced with the use of systems that ... -
Recessionary tales: an investigation into how intellectually disabled young people, and their families, experienced the economic downturn
(NUI Galway, 2018-09-26)This study presents an original contribution to knowledge through investigating the impact and lived experience of economic recession for intellectually disabled young people and their families in Ireland, who use services ... -
Recombinant expression and characterization of ligand binding to mutants ff 3-O-sulphotransferase-1
(2014-10-21)Heparan Sulphate (HS) is a highly charged glycosyaminoglycan (GAG) that is closely related to Heparin, a related GAG with a higher degree of sulphation. Heparin is used in the development of anticoagulant drugs. Currently, ... -
Reconstructive performances of memory and trauma in life writing by daughters of Harkis
(NUI Galway, 2018-12-14)This study presents a close reading and comparative analysis of a corpus of texts by daughters of harkis – Algerian men who served as auxiliary soldiers in the French army during the Algerian War of Independence (1954-1962) ... -
A refined model of nucleolar formation derived from the analysis of UBF variants and the hierarchical silencing of human nucleolar organizer regions
(NUI Galway, 2017-03-23)The nucleolus, the largest sub-nuclear structure, forms around arrays of ribosomal RNA genes, termed nucleolar organizer regions (NORs). As the site of ribosome biogenesis, nucleolar function is intrinsically linked to ... -
Reform, instruction, and practice: the impact of the Catholic Revival on the laity in the Dublin diocese, 1793-1853
(2016-09-14)In the aftermath of the 1793 Catholic Relief Act the Catholic Church in Dublin experienced a period of revival. The building of new churches, the flourishing of religious orders, and the development Sunday Schools all point ... -
Regional development in minority language territories: state policies, structures and interventions in the Irish Gaeltacht
(2016-09-09)The primary aim of this thesis was to critically assess the capacity of the state to conceptualise and implement policies in support of the sustainable development of the Gaeltacht, and to do so through an integrated spatial ... -
Regional Scale Modelling of Boundary Layer Ozone and Influences of Climate Change
(2013-02-20)Ozone is a major air quality parameter, a key player in atmospheric chemistry and instrumental in greenhouse gas forcing. Consequently, the subject of ozone pollution warrants significant consideration in the construction ... -
Regulation and assembly of the associated network in human cells
(2011-10)Centromeres are the chromosomal loci which are responsible for the equal segregation of sister chromatids to daughter cells during mitosis, by directing the assembly of kinetochores. Despite being involved in the faithful ... -
Regulation and function of the tumour suppressor 53BP1 at sites of DNA damage
(2013-10-16)Cancer is the major cause of death for people in middle age. It results from cell transformation into malignant cells and propagates with normal controls. This process is induced by mutations occurring in DNA through the ...