Now showing items 1-6 of 6

    • Analysis of cytokine expression in breast cancer 

      Hartmann, Marion Charlotte (2014-10-29)
      Introduction: It has long been recognized that cancer develops in sites of chronic inflammation. Tumours seem to seize molecular pathways seen in wound healing and the inflammatory response and as a consequence appear as ...
    • Clinical Applications of Molecular Profiling in Colorectal Cancer 

      Kheirelseid, Elrasheid Ahmed Hassan (2011-06)
      Despite developments in diagnosis and treatment, 20% of colorectal cancer (CRC) patients present with metastatic disease and 30% of cases recur after curative surgery. Furthermore, the molecular factors involved in prognosis ...
    • Integration of Genetic Biomarkers in Prognostic Models for Breast Cancer Survival 

      Wall, Deirdre (2014-01-08)
      The main aim of my PhD is to create a prognostic model for invasive breast cancer patients for disease recurrence and death. The data were collected retrospectively and are comprised of 647 invasive breast cancer patients ...
    • Meseanchymal stem cell mediated sodium iodide symporter gene therapy of breast cancer 

      Ryan, James John (2014-05-07)
      Introduction: The Sodium Iodide Symporter (NIS) facilitates iodide accumulation in the thyroid and radioiodide imaging and treatment of thyroid disease. Studies have suggested that elevated levels of NIS expression in ...
    • Metastatic breast cancer: Patterns of metastasis and novel biomarkers 

      McAnena, Peter (NUI Galway, 2018-05-25)
      Breast cancer is a heterogeneous disease and is the leading cause of cancer-related deaths among women, with metastatic disease the principle cause of mortality. In recent years great advances have been made in stratifying ...
    • MiRNAs as oncologic biomarkers for breast cancer 

      McDermott, Ailbhe (2014-08-18)
      Understanding of the molecular complexity underlying breast cancer has greatly advanced in recent years. Distinct phenotypic subtypes have been identified each of which carry prognostic and predictive implications. Despite ...