Now showing items 1-2 of 2

    • Host recognition of bacterial muramyl dipeptide mediated through nod2 

      Inohara, Naohiro; Ogura, Yasunori; Fontalba, Ana; Gutierrez, Olga; Pons, Fernando; Crespo, Javier; Fukase, Koichi; Inamura, Seiichi; Kusumoto, Shoichi; Hashimoto, Masahito; Foster, Simon J.; Moran, Anthony P.; Fernandez-Luna, Jose L.; Nuñez, Gabriel (American Society for Biochemistry & Molecular Biology (ASBMB), 2003-01-04)
      NOD2, a protein associated with susceptibility to Crohn's disease, confers responsiveness to bacterial preparations of lipopolysaccharide and peptidoglycan, but the precise moiety recognized remains elusive. Biochemical ...
    • Regulatory regions and critical residues of nod2 involved in muramyl dipeptide recognition 

      Tanabe, Tsuyoshi; Chamaillard, Mathias; Ogura, Yasunori; Zhu, Li; Qiu, Su; Masumoto, Junya; Ghosh, Partho; Moran, Anthony; Predergast, Martina M; Tromp, Gerard; Williams, Charlene J; Inohara, Naohiro; Núñez, Gabriel (Wiley-Blackwell, 2004-03-25)
      Multiple genetic variants of CARD15/NOD2 have been associated with susceptibility to Crohn's disease and Blau syndrome. NOD2 recognizes muramyl dipeptide (MDP) derived from bacterial peptidoglycan (PGN), but the molecular ...